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Source: Zhejiang Ocean University

Zhejiang Ocean University Releases 'Huangxin No. 1' Breeding Chip for Large Yellow Croaker

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Monday, February 09, 2026, 02:00 (GMT + 9)

Breakthrough genotyping technology creates a “genetic ID card,” boosting precision breeding and accelerating high-quality development of China’s large yellow croaker industry

Recently, a research team led by Professor Yan Xiaojun, Party Secretary of Zhejiang Ocean University, announced the successful development of a liquid-phase breeding chip named “Huangxin No. 1” for large yellow croaker. Developed in collaboration with multiple research institutions, the chip is based on genotyping technology and establishes a precise “genetic ID card” for the species. The innovation directly addresses long-standing industry challenges such as mixed germplasm, unclear seed sources, and lengthy breeding cycles, injecting new momentum into the high-quality development of China’s large yellow croaker aquaculture industry.

The large yellow croaker is one of China’s most important marine aquaculture species. Among them, croakers from the Zhoushan waters, particularly the Daiqu grouper population and its prized “Golden Strain”—distinguished by an entirely golden body color—are highly favored by the market for their attractive appearance and excellent taste. However, the industry has long struggled with low breeding efficiency and unstable traits.
“There is a relative lack of high-quality, locally sourced large yellow croaker fry in Zhoushan,” said Yan Xiaojun. “Traditional breeding relies heavily on manual observation, which is time-consuming and unstable, leading to issues such as golden body color degradation and uncertain germplasm origins.”

To fundamentally resolve these issues, Yan Xiaojun’s team launched a systematic breeding program for high-quality native large yellow croaker seedlings in 2019. Over several years, the team successfully selected parental lines with stable genetic traits, forming the basis for further innovation. Focusing on the key economic trait of body color, the researchers developed the “Huangxin No. 1” breeding chip. Unlike previous chips that mainly targeted disease resistance or muscle quality, “Huangxin No. 1” is the first breeding chip specifically designed to improve body color genetics in large yellow croaker.

Through whole-genome analysis, the team screened 5,509 key genetic loci, enabling targeted capture of critical genomic regions. The chip not only accurately identifies populations and strains but also integrates functionally related loci associated with body color, significantly improving screening efficiency for golden traits. With an identification accuracy of 80%–90%, the chip effectively solves the problem of unclear seedling identification and can shorten the breeding cycle of superior strains by more than 30%, achieving faster and more precise selection.

<-- Source: Zhejiang Ocean University

Yan Xiaojun explained: “First, it helps establish germplasm records, providing reliable molecular evidence for stock enhancement and seedling traceability. Second, it allows us to optimize economic traits by directly screening genes related to golden body color and rapid growth, greatly enhancing breeding efficiency.”

Behind this compact chip is a strong foundation of industry–academia–research integration. “Huangxin No. 1” was developed on a “breeding–propagation–promotion” integrated platform jointly built by the Zhoushan Fisheries Breeding and Seedling Science and Technology Innovation Center, Zhejiang Ocean University, Zhoushan Fisheries Research Institute, Zhejiang Provincial Marine Fisheries Research Institute, and Zhejiang Zhongwei Science and Technology Innovation Marine Technology Co., Ltd. Field verification in commercial aquaculture populations showed a site detection rate exceeding 99%, demonstrating high stability and practical applicability.

Source: Zhejiang Ocean University

The release of “Huangxin No. 1” provides a more precise, standardized, and traceable technological solution for upgrading the large yellow croaker seed industry. “We hope this technology will drive the industry toward standardization and high quality,” said Yan Xiaojun, “and offer strong seed-industry support for building China’s ‘blue granary’.”


🇯🇵 Japanese(日本語)

浙江海洋大学、「大型黄魚向け育種チップ『Huangxin No. 1』を発表

画期的なジェノタイピング技術が「遺伝子IDカード」を構築し、中国の大型黄魚産業の高品質発展を加速

最近、浙江海洋大学党委書記である Yan Xiaojun教授 が率いる研究チームは、複数の研究機関 と共同で、大型黄魚 向けの液相育種チップ 「Huangxin No. 1」 の開発に成功したと発表した。本チップは ジェノタイピング技術 に基づき、同種に対する精密な 「遺伝子IDカード」 を構築するものであり、種質の混在種苗由来の不明確さ育種周期の長期化 といった業界の長年の課題を根本的に解決し、中国の大型黄魚養殖産業の高品質発展 に新たな原動力を注入する。

大型黄魚中国で最も重要な海洋養殖魚種の一つ である。その中でも、舟山海域 由来の個体、特に 大渠群体 に属する、全身が黄金色を呈する 希少な 「ゴールデン系統」 は、その 美しい外観優れた食味 により市場で高い人気を誇る。しかし、同産業は長年にわたり 育種効率の低さ形質の不安定性 といった問題に直面してきた。
舟山では高品質な在来大型黄魚種苗が相対的に不足しています」と Yan Xiaojun は述べた。「従来の育種は人為的観察に依存しており、周期が長く安定性に欠けるため、黄金色体色の退化や種源不明確化といった問題が顕在化しています」。

これらの問題を根本的に解決するため、Yan Xiaojunの研究チーム2019年高品質な在来大型黄魚種苗の体系的育種計画 を開始した。数年にわたる選抜を経て、遺伝的に安定した親魚系統 を確立し、さらなる技術革新の基盤を築いた。研究チームは 体色という主要な経済形質 に焦点を当て、「Huangxin No. 1」育種チップ を開発した。疾病抵抗性筋肉品質 を重視してきた従来の育種チップとは異なり、「Huangxin No. 1」体色の遺伝的改良を明確に目的とした初の育種チップ である。

全ゲノム解析 により、研究チームは 5,509の主要遺伝子座 を選別し、重要なゲノム領域のターゲット捕捉 を実現した。本チップは 集団や系統の正確な識別 を可能にするだけでなく、体色に関連する 機能的遺伝子座 を統合することで、ゴールデン形質の選抜効率を大幅に向上 させた。識別精度は 80%~90% に達し、種苗識別の不明確さという問題を事実上解決 するとともに、優良系統の育種周期を30%以上短縮 することができる。
Yan Xiaojun は次のように強調した。「第一に、種質資源のファイリング を実現し、増殖放流種苗トレーサビリティ に対する 信頼性の高い分子証拠 を提供します。第二に、経済形質の最適化 を可能にし、黄金体色高速成長 に関連する遺伝子を直接選抜することで、育種効率を飛躍的に高めます。」

この小さなチップの背後には、産学研の深い融合 という強固な基盤がある。「Huangxin No. 1」 は、舟山水産育種・種苗科学技術イノベーションセンター浙江海洋大学舟山水産研究所浙江省海洋水産研究所、および 浙江中威科技創新海洋科技有限公司 が共同で構築した 「育種―繁殖―普及」一体化プラットフォーム から誕生した。実際の養殖現場 での検証により、検出率は99%以上 に達し、高い安定性と実用性 が実証されている。

「Huangxin No. 1」 の発表は、大型黄魚種苗産業の高度化 に向けた より精密で、標準化され、追跡可能な技術手段 を提供するものとなった。
この技術を通じて、大型黄魚産業を標準化と高品質の方向へ着実に導きたい」と Yan Xiaojun は述べ、「中国の『ブルーグラナリー』建設に向けた強力な種業支援を提供したい」と語った。


🇨🇳 Chinese (Simplified)(简体中文)

浙江海洋大学发布“大黄鱼育种芯片‘Huangxin No. 1’”

突破性基因分型技术打造“遗传身份证”,加速中国大黄鱼产业高质量发展

近日,由 浙江海洋大学党委书记 颜晓军教授 领衔的研究团队,联合 多家科研机构,成功研发出一款专用于 大黄鱼 育种的液相芯片——“Huangxin No. 1”。该芯片基于 基因分型技术,为大黄鱼构建精准的 “遗传身份证”,从根本上破解了 种质混杂种苗来源不清育种周期过长 等行业长期瓶颈问题,为 中国大黄鱼养殖产业高质量发展 注入了核心动力。

大黄鱼我国最重要的海水养殖鱼类之一。其中,来自 舟山海域 的大黄鱼,尤其是隶属于 大渠群体全身呈现金黄色 的珍稀 “黄金品系”,因其 外形美观肉质鲜美 而深受市场青睐。然而,该产业长期面临 育种效率低性状不稳定 等挑战。
舟山地区优质本地大黄鱼种苗相对匮乏。”颜晓军 表示,“传统育种主要依赖人工观察,周期长、稳定性差,导致黄金体色退化、种源不清等问题日益突出。”

为从根本上破解产业困境,颜晓军团队2019年 启动了 优质本地大黄鱼种苗系统育种计划。经过多年选育,成功筛选出 遗传性状稳定的亲本群体,为进一步创新奠定了坚实基础。在此基础上,团队聚焦 体色这一关键经济性状,研发出 “Huangxin No. 1”育种芯片。与以往侧重 抗病性肌肉品质 的育种芯片不同,“Huangxin No. 1”首个明确以体色遗传改良为目标的育种芯片

通过 全基因组数据分析,研究团队筛选出 5,509个关键位点,实现了 目标基因区域的精准捕获。该芯片不仅能够准确识别 大黄鱼群体或品系,更通过整合与体色相关的 功能性位点,显著提升了 黄金体色性状的筛选效率。其识别准确率达到 80%–90%,基本解决了 种苗鉴别不清 的问题,并可 将优良品系的育种周期缩短30%以上
颜晓军 进一步强调:“第一是对 种质资源进行‘建档’,为 增殖放流种苗溯源 提供 可靠的分子证据;第二是对 经济性状进行‘优化’,能够直接筛选与 黄金体色快速生长 相关的基因,实现高效育种。”

这枚小小的芯片背后,是 产学研深度融合 的有力支撑。“Huangxin No. 1” 诞生于由 舟山水产育种与种苗科技创新中心浙江海洋大学舟山市水产研究所浙江省海洋水产研究所 以及 浙江中威科技创新海洋科技有限公司 联合构建的 “育种—繁育—推广”一体化平台。在 实际养殖群体 中的验证结果显示,其 位点检测率超过99%,展现出 良好的稳定性和实用性

“Huangxin No. 1” 的发布,为 大黄鱼种业升级 提供了 更加精准、规范且可追溯的技术路径
颜晓军 表示:“希望通过这一技术,推动大黄鱼产业稳步迈向标准化和高质量发展,并为建设我国 ‘蓝色粮仓’ 提供强有力的种业支撑。”

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